Simulations of RNA base pairs in a nanodroplet reveal solvation-dependent stability
نویسندگان
چکیده
منابع مشابه
Simulations of RNA base pairs in a nanodroplet reveal solvation-dependent stability.
We show that RNA base pairs have variable stability depending on their degree of solvation. This finding has far-reaching biological implications for nucleic acid structure in a partially solvated cellular environment such as inside RNA-protein complexes. Molecular dynamics simulations of partially solvated Watson-Crick RNA base pairs show that whereas water serves to destabilize a base pair by...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2007
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0705573104